DNA polymerases BI and D , from the hyperthermophilic archaeon , 1 Pyrococcus furiosus , both bind to PCNA with their C - terminal PIP box 2 motifs . 3 4
نویسندگان
چکیده
* To whom correspondence should be addressed: 15 Yoshizumi ISHINO, Prof. 16 Department of Genetic Resources Technology, 17 Faculty of Agriculture, Kyushu University, 18 6-10-1 Hakozaki, Higashi-ku, Fukuoka-shi, Fukuoka 812-8581, Japan 19 Phone: +81-92-642-4217 20 Fax: +81-92-642-3051 21 E-mail: [email protected] 22 23 Running Title: Interaction of PCNA with Pol B and PolD in Archaea 24 AC CE PT ED Copyright © 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Bacteriol. doi:10.1128/JB.00073-07 JB Accepts, published online ahead of print on 11 May 2007
منابع مشابه
DNA polymerases BI and D from the hyperthermophilic archaeon Pyrococcus furiosus both bind to proliferating cell nuclear antigen with their C-terminal PIP-box motifs.
Proliferating cell nuclear antigen (PCNA) is the sliding clamp that is essential for the high processivity of DNA synthesis during DNA replication. Pyrococcus furiosus, a hyperthermophilic archaeon, has at least two DNA polymerases, polymerase BI (PolBI) and PolD. Both of the two DNA polymerases interact with the archaeal P. furiosus PCNA (PfuPCNA) and perform processive DNA synthesis in vitro....
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